Medical Progress - Statins for people with cardiovascular risk factors: A meta-analysis

The benefits of statin treatment for people without established cardiovascular disease but with risk factors have been confirmed in a meta-analysis.

The meta-analysis included 10 studies and 70,388 subjects. With a mean follow-up of 4.1 years, statin therapy reduced all-cause mortality significantly by 12%. There were also significant reductions in major coronary events (by 30%) and major cerebrovascular events (by 19%).

Statins benefit people without established cardiovascular disease but with risk factors.

Brugts JJ, et al. The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trial. BMJ 2009;339:36